The 32 bit version of Windows XP will usually only open one 16-bit process and put all 16-bit apps running on the system into that process. This is necessary for some older applications that run together and share resources.
But most 16-bit applications work better when they have their own dedicated resources. With the following registry change, the process is put in a "Win16 VDM" (16 bit Virtual DOS Machine) which doesn't allow any interaction with other processes. This is also called a WOW (Windows On Windows) process.
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